Adamts20^bt-Bei1
Spontaneous Allele Detail

Summary

• Symbol: Adamts20^bt-Bei1
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 20; belted 1 David Beier
• MGI ID: MGI:2673334
• Synonyms: bt, bt^bei
• Gene: Adamts20 Location: Chr15:94166177-94329966 bp, - strand Genetic Position: Chr15, 48.2 cM
• Alliance: Adamts20^bt-Bei1 page

Mutation origin

• Strain of Origin: C57BL/6J-ple

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Single point mutation
• Mutation details: This mouse was identified as an allele at the bt locus as it failed to complement a known bt mutant mouse. The mutation was identified as a C to T transition at position 2860 that generates a premature stop codon. This results in a truncated protein that lacks the 471 C-terminal amino acids. (J:84755)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamts20 Mutation: 93 strains or lines available

References

• Original: J:84755 Rao C, et al., A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation. Development. 2003 Oct;130(19):4665-72
• All: 9 reference(s)