Zfpm1^tm3Sho
Targeted Allele Detail

Summary

• Symbol: Zfpm1^tm3Sho
• Name: zinc finger protein, multitype 1; targeted mutation 3, Stuart Orkin
• MGI ID: MGI:2669966
• Synonyms: FOG-1 KI
• Gene: Zfpm1 Location: Chr8:123008880-123063990 bp, + strand Genetic Position: Chr8, 70.86 cM, cytoband E1
• Alliance: Zfpm1^tm3Sho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84538
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A point mutation was introduced altering the PIDLSK motif required for CtBP binding to PIASSK (D814A, L815S). (J:84538)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfpm1 Mutation: 31 strains or lines available

References

• Original: J:84538 Katz SG, et al., Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo. Mol Cell Biol. 2002 May;22(9):3121-8
• All: 1 reference(s)