Sack1g^wly
Spontaneous Allele Detail

Summary

• Symbol: Sack1g^wly
• Name: scaffolding CK1 anchoring protein G; wooly
• MGI ID: MGI:2668878
• Gene: Sack1g Location: Chr11:61574917-61600777 bp, + strand Genetic Position: Chr11, 37.96 cM
• Alliance: Sack1g^wly page

Wooly coat in Sack1g^wly/Sack1g^wly mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: NOD/ShiLtJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: A 955 bp deletion removes part of intron 2 and the splice acceptor site at the beginning of exon 3. This results in incorrect splicing and a premature stop codon leading to a truncated protein. The deletion overlaps with intron 10 of Slc5a10 on the opposite strand but does not affect splicing of that gene. (J:195478)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sack1g Mutation: 24 strains or lines available

References

• Original: J:84609 Ward-Bailey PF, et al., New mouse mutation on Chromosome 11 affecting hair texture. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2003
• All: 3 reference(s)