Epha2^{Gt(U3Betageo)J3A3Rul}
Gene trapped Allele Detail

Summary

• Symbol: Epha2^{Gt(U3Betageo)J3A3Rul}
• Name: Eph receptor A2; gene trap J3A3, H Earl Ruley
• MGI ID: MGI:2668054
• Synonyms: eckⁱ
• Gene: Epha2 Location: Chr4:141028551-141056695 bp, + strand Genetic Position: Chr4, 73.67 cM, cytoband D-E
• Alliance: Epha2^{Gt(U3Betageo)J3A3Rul} page

Mutation origin

• Mutant Cell Line: J3A3
• Germline Transmission: Earliest citation of germline transmission: J:31973
• Parent Cell Line: D3H (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: U3betageo Vector Type: gene trap
• Mutation details: A provirus, containing Betageo, inserted into an intron 1.8 kb downstream of the alternatively spliced exon 5.2. Endogenous protein was undetected in homozygous mutant mice by Western blot analysis. (J:31973, J:151684)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epha2 Mutation: 96 strains or lines available

References

• Original: J:31973 Chen J, et al., Germ-line inactivation of the murine Eck receptor kinase by gene trap retroviral insertion. Oncogene. 1996 Mar 7;12(5):979-88
• All: 3 reference(s)