Ogn^tm1Eta
Targeted Allele Detail

Summary

• Symbol: Ogn^tm1Eta
• Name: osteoglycin; targeted mutation 1, Elena S Tasheva
• MGI ID: MGI:2664973
• Synonyms: Ogn^-
• Gene: Ogn Location: Chr13:49761522-49777977 bp, + strand Genetic Position: Chr13, 25.34 cM
• Alliance: Ogn^tm1Eta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:84062
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo-resistance cassette replaced exon 2 after the His residue at position 28. Northern blots from lungs of homozygous mice were negative for mRNA transcripts from the targeted gene (J:84062)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ogn Mutation: 18 strains or lines available

References

• Original: J:84062 Tasheva ES, et al., Mimecan/osteoglycin-deficient mice have collagen fibril abnormalities. Mol Vis. 2002 Oct 31;8:407-15
• All: 5 reference(s)