Rr320tm1.1Ley
Targeted Allele Detail
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Symbol: |
Rr320tm1.1Ley |
Name: |
regulatory region 320; targeted mutation 1.1, Timothy Ley |
MGI ID: |
MGI:2662828 |
Synonyms: |
Delta HS3/NEO -, Hbb-artm1.1Ley |
Gene: |
Rr320 Location: Chr7:103501973-103526752 bp, + strand Genetic Position: Chr7, Syntenic
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Alliance: |
Rr320tm1.1Ley page
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Germline Transmission: |
Earliest citation of germline transmission:
J:33053
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Parent Cell Line: |
RW-4 (ES Cell)
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Strain of Origin: |
129X1/SvJ
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Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: The loxP site flanked neomycin resistance gene cassette that had replaced the 5' DNase I hypersensitive site 3 (HS3) was removed from Rr320tm1Ley ES cells via transient expression of cre recombinase and transmitted through the germline.
(J:33053)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr320 Mutation: |
0 strains or lines available
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Original: |
J:33053 Hug BA, et al., Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3. Mol Cell Biol. 1996 Jun;16(6):2906-12 |
All: |
2 reference(s) |
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