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Slc15a2tm1Dan
Targeted Allele Detail
Summary
Symbol: Slc15a2tm1Dan
Name: solute carrier family 15 (H+/peptide transporter), member 2; targeted mutation 1, Hannelore Daniel
MGI ID: MGI:2661036
Synonyms: Pept2-, Pept2lacZ
Gene: Slc15a2  Location: Chr16:36570539-36605324 bp, - strand  Genetic Position: Chr16, 25.97 cM
Alliance: Slc15a2tm1Dan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83166
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region of exon 1 was replaced with lacZ. The floxed neo selection cassette was excised in vivo. Northern and Western blot analyses indicated an absence of normal transcript and protein in homozygous mutant mice. Expression of lacZ was driven by the endogenous promoter. (J:83166)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc15a2 Mutation:  64 strains or lines available
References
Original:  J:83166 Rubio-Aliaga I, et al., Targeted disruption of the peptide transporter Pept2 gene in mice defines its physiological role in the kidney. Mol Cell Biol. 2003 May;23(9):3247-52
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory