Nrip1^tm1Mpk
Targeted Allele Detail

Summary

• Symbol: Nrip1^tm1Mpk
• Name: nuclear receptor interacting protein 1; targeted mutation 1, Malcolm Parker
• MGI ID: MGI:2657149
• Synonyms: RIPKO
• Gene: Nrip1 Location: Chr16:76084288-76170715 bp, - strand Genetic Position: Chr16, 43.65 cM
• Alliance: Nrip1^tm1Mpk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:74971
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence following the first 27 amino acids was deleted and replaced with an IRES-lacZ-neo cassette via homologous recombination. (J:74971)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrip1 Mutation: 195 strains or lines available

Notes

The ES cell line used was 129/Ola-derived.

References

• Original: J:74971 White R, et al., The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility. Nat Med. 2000 Dec;6(12):1368-74
• All: 21 reference(s)