Erbb2^tm1Mll
Targeted Allele Detail

Summary

• Symbol: Erbb2^tm1Mll
• Name: erb-b2 receptor tyrosine kinase 2; targeted mutation 1, Ulrich Muller
• MGI ID: MGI:2656906
• Synonyms: Erbb2^flox
• Gene: Erbb2 Location: Chr11:98303310-98328542 bp, + strand Genetic Position: Chr11, 61.75 cM, cytoband D
• Alliance: Erbb2^tm1Mll page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82801
• Parent Cell Line: JM-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites flanking exon 1 were introduced via homologous recombination. (J:82801)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Erbb2 Mutation: 59 strains or lines available

References

• Original: J:82801 Leu M, et al., Erbb2 regulates neuromuscular synapse formation and is essential for muscle spindle development. Development. 2003 Jun;130(11):2291-301
• All: 8 reference(s)