Npy5r^tm1Pern
Targeted Allele Detail

Summary

• Symbol: Npy5r^tm1Pern
• Name: neuropeptide Y receptor Y5; targeted mutation 1, Patrick Ernfors
• MGI ID: MGI:2654579
• Synonyms: Y5^-
• Gene: Npy5r Location: Chr8:67132617-67140746 bp, - strand Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
• Alliance: Npy5r^tm1Pern page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:71826
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: The gene was disrupted by insertion of a lacZ-neo cassette into exon 2 via homologous recombination. Gene expression was absent in homozygous mutant mice as determined by Northern blot analysis of brain RNA. (J:71826)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Npy5r Mutation: 26 strains or lines available

References

• Original: J:71826 Naveilhan P, et al., Distinct roles of the Y1 and Y2 receptors on neuropeptide Y-induced sensitization to sedation. J Neurochem. 2001 Sep;78(6):1201-7
• All: 3 reference(s)