Del(8Atp6v0d1-Agrp)1Rpa
Targeted Allele Detail

Summary

• Symbol: Del(8Atp6v0d1-Agrp)1Rpa
• Name: deletion, Chr 8, Richard D Palmiter 1
• MGI ID: MGI:2653084
• Synonyms: Agrp/Atp6v0d1^tm1Rpa
• Gene: Del(8Atp6v0d1-Agrp)1Rpa Location: unknown Genetic Position: Chr8, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82232
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(8Atp6v0d1-Agrp)1Rpa involves 2 genes/genome features (Atp6v0d1, Agrp) View all
• Mutation details: A 4.7 kb region encompassing exons 2-4 of Agrp and exon 1 of Atp6v0d1 was deleted and replaced with a Ucp10-PGK-neo cassette via homologous recombination. (J:82232)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(8Atp6v0d1-Agrp)1Rpa Mutation: 0 strains or lines available

References

• Original: J:82232 Miura GI, et al., The d subunit of the vacuolar ATPase (Atp6d) is essential for embryonic development. Transgenic Res. 2003 Feb;12(1):131-3
• All: 1 reference(s)