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Targeted Allele Detail
Symbol: Mgmttm1Iz
Name: O-6-methylguanine-DNA methyltransferase; targeted mutation 1, Manfred F Rajewsky
MGI ID: MGI:2652462
Synonyms: AGTflox
Gene: Mgmt  Location: Chr7:136496343-136731995 bp, + strand  Genetic Position: Chr7, 82.07 cM
Alliance: Mgmttm1Iz page
Germline Transmission:  Earliest citation of germline transmission: J:82357
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    The last exon of the gene was flanked by inserted loxP sites. (J:82357)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgmt Mutation:  29 strains or lines available
Original:  J:82357 Schweer T, et al., Conditional liver-specific "knock-out" of the murine genes encoding 06-Alkylguanine-DNA Alkyltransferase (AGT) and AP-Endonuclease (APE). J Biomol Struct Dyn. 1998;16:180-1 (Abstr.)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.24
The Jackson Laboratory