About   Help   FAQ
Mgmttm1Iz
Targeted Allele Detail
Summary
Symbol: Mgmttm1Iz
Name: O-6-methylguanine-DNA methyltransferase; targeted mutation 1, Manfred F Rajewsky
MGI ID: MGI:2652462
Synonyms: AGTflox
Gene: Mgmt  Location: Chr7:136496343-136731995 bp, + strand  Genetic Position: Chr7, 82.07 cM
Alliance: Mgmttm1Iz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82357
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    The last exon of the gene was flanked by inserted loxP sites. (J:82357)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgmt Mutation:  29 strains or lines available
References
Original:  J:82357 Schweer T, et al., Conditional liver-specific "knock-out" of the murine genes encoding 06-Alkylguanine-DNA Alkyltransferase (AGT) and AP-Endonuclease (APE). J Biomol Struct Dyn. 1998;16:180-1 (Abstr.)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
07/05/2024
MGI 6.24
The Jackson Laboratory