About   Help   FAQ
Targeted Allele Detail
Symbol: S100btm1Ito
Name: S100 protein, beta polypeptide, neural; targeted mutation 1, Shigeyoshi Itohara
MGI ID: MGI:2451049
Gene: S100b  Location: Chr10:76089687-76096993 bp, + strand  Genetic Position: Chr10, 38.76 cM
Alliance: S100btm1Ito page
Germline Transmission:  Earliest citation of germline transmission: J:81786
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 2 and part of exon 3 were replaced with a floxed neomycin resistance cassette via homologous recombination. Absence of gene expression was confirmed by Northern blot and immunohistochemical analysis. (J:81786)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any S100b Mutation:  9 strains or lines available
Original:  J:81786 Nishiyama H, et al., Glial protein S100B modulates long-term neuronal synaptic plasticity. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):4037-42
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory