Gt(ROSA)26Sor^{tm1.1(EYFP)Cos}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(EYFP)Cos}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Frank Costantini
• MGI ID: MGI:2449041
• Synonyms: deltaNeo-YFP, R26R-YFP cre, ROSA-YFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(EYFP)Cos} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80963
• Parent Cell Line: JM-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

Allele Type: Targeted (Reporter) Mutation: Insertion Mutation details: The floxed PGK-neo cassette was deleted by mating Gt(ROSA)26Sor^tm1(EYFP)Cos animals to the Tg(ACTB-cre)2Mrt line. Removal of the tpA stop sequence within the floxed neo cassette allows transcription of the EYFP reporter gene. (J:80963, J:98830)

Generation of Gt(ROSA)26Sor^tm1(EYFP)Cos or Gt(ROSA)26Sor^tm2(ECFP)Cos.

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:80963 Srinivas S, et al., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol. 2001;1(1):4
• All: 31 reference(s)