Tg(HLA-B)1Chmb
Transgene Detail

Summary

• Symbol: Tg(HLA-B)1Chmb
• Name: transgene insertion 1, Jeffrey W Chamberlain
• MGI ID: MGI:2447795
• Synonyms: HLA-A2^nat
• Transgene: Tg(HLA-B)1Chmb Location: unknown
• Alliance: Tg(HLA-B)1Chmb page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• A 6 kb genomic DNA fragment containing the entire human HLA-B7 gene was used for the transgene. (J:80678)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:80678 Borenstein SH, et al., CD8+ T cells are necessary for recognition of allelic, but not locus-mismatched or xeno-, HLA class I transplantation antigens. J Immunol. 2000 Sep 1;165(5):2341-53
• All: 2 reference(s)