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Tg(Mpz)80.2Wra
Transgene Detail
Summary
Symbol: Tg(Mpz)80.2Wra
Name: transgene insertion 80.2, Lawrence Wrabetz
MGI ID: MGI:2447694
Synonyms: Tg80.2
Transgene: Tg(Mpz)80.2Wra  Location: unknown  
Alliance: Tg(Mpz)80.2Wra page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Mpz)80.2Wra expresses 1 gene
 
Mutation detailsThe entire Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation signal) was used as the transgene. Line 80.2 carries over 31 copies of the integrated transgene and expression is approximately 7.3-fold that of the endogenous protein. (J:78758)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:78758 Wrabetz L, et al., P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. J Cell Biol. 2000 Mar 6;148(5):1021-34
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory