Tg(Pcp2-TAg)4Horr
Transgene Detail

Summary

• Symbol: Tg(Pcp2-TAg)4Horr
• Name: transgene insertion 4, Harry T Orr
• MGI ID: MGI:2389407
• Synonyms: SV4
• Transgene: Tg(Pcp2-TAg)4Horr Location: unknown
• Alliance: Tg(Pcp2-TAg)4Horr page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The SV40 t and T antigen coding region was ligated to the murine Pcp2 promoter region. The Pcp2 promoter restricted expression to Purkinje cells. The founder line carried 10 copies of the transgenic construct. (J:79857)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:79857 Feddersen RM, et al., Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice. Neuron. 1992 Nov;9(5):955-66
• All: 3 reference(s)