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Sbnt2C57BL/6J
QTL Variant Detail
Summary
QTL variant: Sbnt2C57BL/6J
Name: spacial bias during navigation task 2; C57BL/6J
MGI ID: MGI:2389319
QTL: Sbnt2  Location: unknown  Genetic Position: Chr13, cM position of peak correlated region/allele: 24.5 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:75894

26 C57BL/6J x DBA/2J (BXD) recombinant inbred (RI) strains were analyzed for loci linked to spatial abilities during the Morris navigation task. 118 polymorphic markers at an average spacing of 25 cM were screened in 6 animals of each RI strain. A locus with significant linkage to escape latencies during the Morris navigation task, Elnt, mapped to mouse Chromosome 1 with a maximun LOD = 6.23 between 90 cM (D1Mit106) - 98 cM (D1Mit155). A locus linked to spacial bias during the Morris navigation task, Sbnt1, mapped to mouse Chromosome 5 with a LOD peak of 3.72 at 61 cM between Spp1 (56 cM) and D5MitByu (68 cM). Two other loci affecting spacial bias were shown to interact with Sbnt1, one of which reached statistcal significance on mouse Chromosome 13 with LOD = 3.41 between 23 cM (D13Byu1) - 35 cM (D13Mit13) and was named Sbnt2. The other locus reached suggestive significance on mouse Chromosome 2 with LOD = 2.9 at 49 cM between D2Mc2 (48 cM) and D2Byu3 (69 cM).

References
Original:  J:75894 Milhaud JM, et al., Two QTLs located on chromosomes 1 and 5 modulate different aspects of the performance of mice of the B x D Ty RI strain series in the Morris navigation task. Behav Genet. 2002 Jan;32(1):69-78
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory