Hoxb4^tm1Nrm
Targeted Allele Detail

Summary

• Symbol: Hoxb4^tm1Nrm
• Name: homeobox B4; targeted mutation 1, Nancy R Manley
• MGI ID: MGI:2388364
• Synonyms: Hoxb4^PolII
• Gene: Hoxb4 Location: Chr11:96209093-96212464 bp, + strand Genetic Position: Chr11, 59.83 cM
• Alliance: Hoxb4^tm1Nrm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:71389
• Parent Cell Line: CC1.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette into the first coding exon 39 bp from the translation initiation codon. (J:71389)

Expression

In Mice Carrying this Mutation:	15 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxb4 Mutation: 18 strains or lines available

References

• Original: J:71389 Manley NR, et al., Hoxb2 and hoxb4 act together to specify ventral body wall formation. Dev Biol. 2001 Sep 1;237(1):130-44
• All: 2 reference(s)