Tg(Ckmm-Dmd)1Chmb
Transgene Detail

Summary

• Symbol: Tg(Ckmm-Dmd)1Chmb
• Name: transgene insertion 1, Jeffrey S Chamberlain
• MGI ID: MGI:2387967
• Transgene: Tg(Ckmm-Dmd)1Chmb Location: unknown
• Alliance: Tg(Ckmm-Dmd)1Chmb page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ckmm-Dmd)1Chmb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Dmd (MGI:94909)

• Mutation details: A full-length mouse Dmd cDNA fused to Ckmm regulatory sequences (6.5 kb including the promoter/enhancer, exon 1, intron 1 and part of exon 2) was used to drive transgene expression in muscle tissue. Expression of the transgene in cardiac and skeletal muscle was confirmed by Western blot analysis. (J:14332)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:14332 Cox GA, et al., Overexpression of dystrophin in transgenic mdx mice eliminates dystrophic symptoms without toxicity [see comments]. Nature. 1993 Aug 19;364(6439):725-9
• All: 1 reference(s)