Epor^tm1Jtp
Targeted Allele Detail

Summary

• Symbol: Epor^tm1Jtp
• Name: erythropoietin receptor; targeted mutation 1, Josef T Prchal
• MGI ID: MGI:2386086
• Gene: Epor Location: Chr9:21870193-21874802 bp, - strand Genetic Position: Chr9, 7.93 cM
• Alliance: Epor^tm1Jtp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67205
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Null/knockout, RMCE-ready)
• Mutations: Insertion, Intragenic deletion
• A PGK-Hprt minigene replaced all eight exons. (J:67205)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epor Mutation: 25 strains or lines available

References

• Original: J:67205 Divoky V, et al., Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor gene. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):986-91
• All: 1 reference(s)