Tpi1^a-M5Neu
Chemically induced Allele Detail

Summary

• Symbol: Tpi1^a-M5Neu
• Name: triosephosphate isomerase 1; mutation 5, Neuherberg
• MGI ID: MGI:2384551
• Synonyms: Tpi-1^r
• Gene: Tpi1 Location: Chr6:124787549-124791121 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: Tpi1^a-M5Neu page

Mutation origin

• Strain of Origin: (101/El x C3H/El)F1

Mutation description

• Allele Type: Chemically induced (other) (Not Applicable)
• Mutation: Undefined
• Mutation details: This mutation results in increased enzymatic activity; heterozygotes have mean activities of 140% of wild-type and homozygotes have 190% of wild-type activity. (J:11280)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tpi1 Mutation: 23 strains or lines available

Notes

The mutation was procarbazine induced.

References

• Original: J:11280 Merkle S, et al., A mutation resulting in increased triosephosphate isomerase activity in Mus musculus. Genet Res. 1991 Apr;57(2):139-45
• All: 1 reference(s)