Ugt8atm1Wst
Targeted Allele Detail
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Symbol: |
Ugt8atm1Wst |
Name: |
UDP galactosyltransferase 8A; targeted mutation 1, Wilhelm Stoffel |
MGI ID: |
MGI:2384084 |
Synonyms: |
cgt- |
Gene: |
Ugt8a Location: Chr3:125658920-125732268 bp, - strand Genetic Position: Chr3, 54.68 cM, cytoband E3-F1
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Alliance: |
Ugt8atm1Wst page
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Ugt8atm1Wst/Ugt8atm1Wst with wild type littermate
Show the 2 phenotype image(s) involving this allele.
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Insertion
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Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette into exon 1 via homologous recombination. In situ hybridization of brain sections using an antisense RNA probe to the gene verified the absence of gene expression in homozygous mutant animals. Galactosyl transferase assays of brain samples from homozygous mutant animals did not detect enzymatic activity.
(J:36558)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ugt8a Mutation: |
28 strains or lines available
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Original: |
J:36558 Bosio A, et al., Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13280-5 |
All: |
7 reference(s) |
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