Ceacam9^tm1Wzm
Targeted Allele Detail

Summary

• Symbol: Ceacam9^tm1Wzm
• Name: CEA cell adhesion molecule 9; targeted mutation 1, Wolfgang Zimmermann
• MGI ID: MGI:2183316
• Synonyms: Ceacam9-
• Gene: Ceacam9 Location: Chr7:16455854-16460035 bp, + strand Genetic Position: Chr7, 9.15 cM
• Alliance: Ceacam9^tm1Wzm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77648
• Parent Cell Line: BALB/c-I (ES Cell)
• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: All of exon 1 and two-thirds of exon 2 were replaced with a neomycin selection cassette. Neither full-length nor truncated transcripts were detected by Northern blot analysis of total placental RNA obtained from homozygous mutant embyros. The absence of transcript was further verified by in situ hybridization. (J:77648)

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ceacam9 Mutation: 16 strains or lines available

References

• Original: J:77648 Finkenzeller D, et al., Trophoblast cell-specific carcinoembryonic antigen cell adhesion molecule 9 is not required for placental development or a positive outcome of allotypic pregnancies. Mol Cell Biol. 2000 Oct;20(19):7140-5
• All: 2 reference(s)