P2ry1^tm1Gac
Targeted Allele Detail

Summary

• Symbol: P2ry1^tm1Gac
• Name: purinergic receptor P2Y, G-protein coupled 1; targeted mutation 1, Christian Gachet
• MGI ID: MGI:2181709
• Synonyms: P2Y1-
• Gene: P2ry1 Location: Chr3:60910216-60916403 bp, + strand Genetic Position: Chr3, 29.24 cM, cytoband E1
• Alliance: P2ry1^tm1Gac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:59055
• Parent Cell Line: P1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• The insertion of a neomycin cassette at nucleotide 3208 disrupted the coding region. (J:59055)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any P2ry1 Mutation: 31 strains or lines available

References

• Original: J:59055 Leon C, et al., Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice [see comments]. J Clin Invest. 1999 Dec;104(12):1731-7
• All: 14 reference(s)