Pdcd6^tm1Hua
Targeted Allele Detail

Summary

• Symbol: Pdcd6^tm1Hua
• Name: programmed cell death 6; targeted mutation 1, Hua Gu
• MGI ID: MGI:2180799
• Synonyms: alg-2^-
• Gene: Pdcd6 Location: Chr13:74451628-74465699 bp, - strand Genetic Position: Chr13, 40.15 cM
• Alliance: Pdcd6^tm1Hua page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:76789
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a neomycin resistance cassette into exon 1 via homologous recombination. Northern and Western blot analysis confirmed the absence of gene expression in thymocytes of homozygous mutant mice. (J:76789)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd6 Mutation: 18 strains or lines available

References

• Original: J:76789 Jang IK, et al., Apoptosis-linked gene 2-deficient mice exhibit normal T-cell development and function. Mol Cell Biol. 2002 Jun;22(12):4094-100
• All: 1 reference(s)