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Allele Detail
Symbol: Gpi1a
Name: glucose-6-phosphate isomerase 1; a variant
MGI ID: MGI:2177271
Gene: Gpi1  Location: Chr7:33900755-33929761 bp, - strand  Genetic Position: Chr7, 19.46 cM
Alliance: Gpi1a page
Strain of Origin:  Not Applicable
Allele Type:    Not Applicable
Mutation:    Nucleotide substitutions
Mutation detailsThis allele determines a slower migrating variant of the encoded enzyme and occurs in the wild and in strains 101/H, A/HeJ, AKR/J, BALB/cJ, C57BR/cdJ, C58/J, CE/J, DBA/2J, DE/J, DW/J, LP/J, MA/J, NZB, PL/J, P/J, RARF, RF/J, SJL/J, ST/bJ, and 129/J. Sequencing analysis identified four nucleotide differences between this allele and Gpi1b. Two differences are silent, while a third difference at position nucleotide position 282 predicts an aspartate for the a allele and an asparagine for the b allele at amino acid position 94. A fourth difference in the 3' untranslated region was also noted. (J:28033)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 14 strains available      Cell Lines: 0 lines available
Carrying any Gpi1 Mutation:  56 strains or lines available
Original:  J:5141 DeLorenzo RJ, et al., Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem Genet. 1969 Apr;3(2):151-62
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.22
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