|
Symbol: |
Gpi1b |
Name: |
glucose-6-phosphate isomerase 1; b variant |
MGI ID: |
MGI:2177270 |
Gene: |
Gpi1 Location: Chr7:33900755-33929761 bp, - strand Genetic Position: Chr7, 19.46 cM
|
Alliance: |
Gpi1b page
|
|
Strain of Origin: |
Not Applicable
|
|
Allele Type: |
|
Not Applicable |
Mutation: |
|
Nucleotide substitutions
|
|
|
Mutation details: This allele determines a faster migrating variant of the encoded enzyme and occurs in the wild and in strains BUB/Bn, CBA/J, CBA/CaJ, C3H/HeH, C3Heb/FeJ, C57BL/6J, C57BL/6J-ob, SEA/GJ and SWR/J. Sequencing analysis identified four nucleotide differences between this allele and Gpi1a. Two differences were silent, while a third difference at nucleotide position 282 predicts an aspartate for the a allele and an asparagine for the b allele at amino acid position 94. A fourth difference in the 3' untranslated region was also noted.
(J:28033)
|
|
|
|
Original: |
J:5141 DeLorenzo RJ, et al., Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus). Biochem Genet. 1969 Apr;3(2):151-62 |
All: |
14 reference(s) |
|