Igf1q1^DBA/2
QTL Variant Detail

Summary

• QTL variant: Igf1q1^DBA/2
• Name: insulin-like growth factor 1 QTL 1; DBA/2
• MGI ID: MGI:2157894
• QTL: Igf1q1 Location: unknown Genetic Position: Chr10, Syntenic

Variant origin

• Strain of Specimen: DBA/2

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:66233

QTLs effecting body weight, obesity and muscle weight were found on mouse Chromosomes 1, 4, 5, 7, 11, 12, 13, and 17 and for leptin on 14 and insulin on chromosome 4. The cross used in the genome wide scan included approximately 400 F2 mice from a (DU6i x DBA/2)F1 intercross. DU6i is a strain selected for high body weight. 93 microsatellite markers were analyzed in the genome wide scan. Locations of the QTLs were provided by the authors and may not be equivalent to the closest microsatellites. Insulin-like growth factor 1 QTL 1 and spleen weight QTL 5 were mapped to mouse Chromosome 10 to cM positions 38 and 64 respectively.

References

• Original: J:66233 Brockmann GA, et al., Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice. Genome Res. 2000 Dec;10(12):1941-57
• All: 1 reference(s)