Szv2^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Szv2^C57BL/6J
• Name: seizure severity 2; C57BL/6J
• MGI ID: MGI:2156837
• QTL: Szv2 Location: unknown Genetic Position: Chr7, cM position of peak correlated region/allele: 64.3 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased kainic acid induced seizure severity compared to DBA/2J. (J:38888)
• Inheritance: Other (see notes)

Notes

Szv2 exhibits additive inheritance.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:38888

In a population of F2 mice derived from B6D2F1 x B6D2F1 hybrids the quantitative trait locus seizure severity 2 Szv2 was mapped to mouse Chromosome 7 near D7Mit66.

References

• Original: J:38888 Ferraro TN, et al., Mapping murine loci for seizure response to kainic acid. Mamm Genome. 1997 Mar;8(3):200-8
• All: 1 reference(s)