Mlviq1^C57BL/6By
QTL Variant Detail

Summary

• QTL variant: Mlviq1^C57BL/6By
• Name: murine leukemia virus infection QTL, 1; C57BL/6By
• MGI ID: MGI:2156824
• QTL: Mlviq1 Location: unknown Genetic Position: Chr7, cM position of peak correlated region/allele: 88.85 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6By

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:43753

Quantitative trait loci (QTL) associated with differences in the immune response during the acute phase of E-55+ murine leukemia virus infection were identified. One candidate locus Mlviq1, was mapped to mouse Chromosome 7 by CXB (BALB/cBy x C57BL/6By) recombinant inbred strain linkage analysis. BALB represents the progressor strain (requiring CD8+ cells to decrease virus burden) and C57BL represents the long term nonprogressor strain (not requiring CD8+ cells).

References

• Original: J:43753 Panoutsakopoulou V, et al., Differences in the immune response during the acute phase of E-55+ murine leukemia virus infection in progressor BALB and long term nonprogressor C57BL mice. J Immunol. 1998 Jul 1;161(1):17-26
• All: 1 reference(s)