Rigs1^C57BL/6J
QTL Variant Detail

Summary

• QTL variant: Rigs1^C57BL/6J
• Name: radiation induced gastroschisis 1; C57BL/6J
• MGI ID: MGI:2156783
• QTL: Rigs1 Location: Chr7:36280015-92394346 bp Genetic Position: Chr7, cM position of peak correlated region/allele: 35.19 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: C57BL/6J

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers decreased risk of radiation-induced gastroschisis.
• Inheritance: Dominant

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:52090

The authors have mapped radiation induced gastroschisis (abdominal wall defect) QTL using genome wide microsatellite typing for markers in a group of mice with gastroschisis to mouse Chromosome 7. At least one of the loci responsible for this trait maps close to D7Mit195 (linkage p = 0.00082) encompassing the interval D7Mit227 and D7Mit148.

References

• Original: J:52090 Hillebrandt S, et al., A locus for radiation-induced gastroschisis on mouse Chromosome 7. Mamm Genome. 1998 Dec;9(12):995-7
• All: 1 reference(s)