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Mol1C57BL/6ByJ
QTL Variant Detail
Summary
QTL variant: Mol1C57BL/6ByJ
Name: modifier of LPS-response 1; C57BL/6ByJ
MGI ID: MGI:2156745
QTL: Mol1  Location: unknown  Genetic Position: Chr7, Syntenic
Variant
origin
Strain of Specimen:  C57BL/6ByJ
Variant
description
Allele Type:    QTL
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:58921

The difference in the response to LPS (lipopolysaccharide) exhibited between C57BL/6J and A/J mice allowed for the mapping of QTls in AXB/BXA Recombinant Inbred strains. Four provisional modifers of the LPS response were mapped to mouse Chromosomes 1, 7, 11, and 13. Mol1 was localized to a 5 cM region flanked by markers D7Mit267 and D7Mit25. Moreover congenic strain B6.C-H24cGpia/By HW24) expresed the Mol1 phenotype within a donor region that included markers D7Mit77, H24, and D7Mit310.

References
Original:  J:58921 Matesic LE, et al., Mapping lipopolysaccharide response loci in mice using recombinant inbred and congenic strains. Genomics. 1999 Nov 15;62(1):34-41
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory