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QTL Variant Detail
QTL variant: Pact1SJL/Bm
Name: platelet activation 1; SJL/Bm
MGI ID: MGI:2155460
QTL: Pact1  Location: unknown  Genetic Position: Chr3, cM position of peak correlated region/allele: 29.17 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Strain of Specimen:  SJL/Bm
Allele Type:    QTL
Inheritance:    Not Specified

Mapping and Phenotype information for this QTL, its variants and associated markers


Linkage analysis was performed on 14 SWXJ (SWR/Bm x SJL/Bm) recombinant inbred strains and 20 AKXD (AKR/J x DBA/2J) recombinant inbred strains to identify QTLs associated with platelet activation. Parental strains SJL/Bm and AKR/J exhibit high levels of spontaneous platelet activation compared to parental strains SWR/Bm and DBA/2J. Linkage to the platelet activation phenotype mapped to approximately 27 cM on mouse Chromosome 3 and is named Pact1 (platelet activation 1). Pact1 is linked to D3Mit7 in the SWXJ RI strains and is linked to D3Nds1 in the AKR/J RI strains.

Original:  J:43555 Ault KA, et al., Genetic control of platelet activation in inbred mouse strains. Platelets. 1997;8(4):235-241
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.22
The Jackson Laboratory