About   Help   FAQ
QTL Variant Detail
QTL variant: Alcp3DBA/2J
Name: alcohol preference locus 3, male specific; DBA/2J
MGI ID: MGI:2155375
QTL: Alcp3  Location: Chr3:147736935-147737065 bp  Genetic Position: Chr3, cM position of peak correlated region/allele: 72.41 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Strain of Specimen:  DBA/2J
Allele Type:    QTL
Mutation:    Undefined
    This allele decreases alcohol preference in male animals compared to C57BL/6J. (J:52086)
Inheritance:    Dominant
View phenotypes and curated references for all genotypes (concatenated display).

Mapping and Phenotype information for this QTL, its variants and associated markers


Backcross progeny from two sets of crosses between (C57BL/6J x DBA/2J)F1 females x C57BL/6J males (N1 = 262 and N2 = 82) and C57BL/6J females x (C57BL/6J x DBA/2J)F1 males (N1= 73 N2 = 78) were analyzed for alcohol consumption. The difference in alcohol consumption between male and female backcross progeny is significant. Therefore sexes were analyzed separately using chi-square analysis to find quantitative trait loci (QTL). P<0.003 was obtained for linkage with D3Mit200 in males.

Original:  J:52086 Peirce JL, et al., A major influence of sex-specific loci on alcohol preference in C57Bl/6 and DBA/2 inbred mice. Mamm Genome. 1998 Dec;9(12):942-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory