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Mop3DBA/2J
QTL Variant Detail
Summary
QTL variant: Mop3DBA/2J
Name: morphine preference 3; DBA/2J
MGI ID: MGI:2154237
QTL: Mop3  Location: Chr1:167756737-189303617 bp  Genetic Position: Chr1, Syntenic
Variant
origin
Strain of Specimen:  DBA/2J
Variant
description
Allele Type:    QTL
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:17972

Morphine consumption was assessed in 606 F2 mice from a C57BL/6J x DBA/2J intercross. A subset of the 606 progeny were tested for QTL (quantitative trait analysis).

QTL Mop3 mapped between D1Mit16 and D1Mit17 on Chromosome 1 with a lod score of 3.0.

This QTL correlated with a small, but detectable decrease in the preference for morphine consumption.

References
Original:  J:17972 Berrettini WH, et al., Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains [see comments]. Nat Genet. 1994 May;7(1):54-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory