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Laq1C57BL/6
QTL Variant Detail
Summary
QTL variant: Laq1C57BL/6
Name: lupus associated arthritis quantitative trait locus 1; C57BL/6
MGI ID: MGI:2154173
QTL: Laq1  Location: unknown  Genetic Position: Chr1, Syntenic
Variant
origin
Strain of Specimen:  C57BL/6
Variant
description
Allele Type:    QTL
Inheritance:    Dominant
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:45708

The authors map D19Mit72 to mouse Chromosome 1, 26.9 cM telomeric to D1Mit15 and 7.8 cM acromeric to D1Nds7 in disagreement with the conventional mapping of this locus on mouse Chromosome 19. A quantitative trait locus associated with inflammatory arthritis Laq1 was mapped in (C57BL/6-Tnfrsf6lpr x MRL-Tnfrsf6lpr)F2 progeny which correlates with D19Mit72 on mouse Chromosome 1. D19Mit72 has been renamed D1Mit1001.

References
Original:  J:45708 Vidal S, et al., Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice. J Clin Invest. 1998 Feb 1;101(3):696-702
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory