Otx1tm2(otd)Asim
Targeted Allele Detail
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Symbol: |
Otx1tm2(otd)Asim |
Name: |
orthodenticle homeobox 1; targeted mutation 2, Antonio Simeone |
MGI ID: |
MGI:2153199 |
Synonyms: |
otd1 |
Gene: |
Otx1 Location: Chr11:21944764-21952897 bp, - strand Genetic Position: Chr11, 14.1 cM
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Alliance: |
Otx1tm2(otd)Asim page
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Germline Transmission: |
Earliest citation of germline transmission:
J:47899
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Parent Cell Line: |
HM-1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd-Hprt1b-m3
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Allele Type: |
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Targeted (Inserted expressed sequence, Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A full length cDNA encoding the Drosphila orthodenticle (otd) gene replaced a 2.3kb fragment containing exons 1 and 2. Correct expression of the Drosophila gene under the control of the Otx1 promoter was verified by in situ hybridization on sagittal sections of a E12.5 embryo.
(J:47899)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Otx1 Mutation: |
85 strains or lines available
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Original: |
J:47899 Acampora D, et al., Murine Otx1 and Drosophila otd genes share conserved genetic functions required in invertebrate and vertebrate brain development. Development. 1998 May;125(9):1691-702 |
All: |
1 reference(s) |
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