Map1b^{Gt(IRESBetageo)2Pgr}
Gene trapped Allele Detail

Summary

• Symbol: Map1b^{Gt(IRESBetageo)2Pgr}
• Name: microtubule-associated protein 1B; gene trap 2, Peter Gruss
• MGI ID: MGI:2148182
• Synonyms: MAP1B^-
• Gene: Map1b Location: Chr13:99557954-99653048 bp, - strand Genetic Position: Chr13, 52.9 cM
• Alliance: Map1b^{Gt(IRESBetageo)2Pgr} page

Mutation origin

• Mutant Cell Line: XVI-78
• Germline Transmission: Earliest citation of germline transmission: J:66509
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pSABetageo Vector Type: gene trap
• Mutation details: The insertion of the gene-trap vector occurred in the intron between exons 1 and 2. This corresponds to downstream of the first 95 amino acids of the Mtap1b gene. This allele is a hypomorph. (J:65509)

Expression

In Mice Carrying this Mutation:	34 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map1b Mutation: 85 strains or lines available

References

• Original: J:40076 Chowdhury K, et al., Evidence for the stochastic integration of gene trap vectors into the mouse germline. Nucleic Acids Res. 1997 Apr 15;25(8):1531-6
• All: 14 reference(s)