Tg(KRT16/KRT14)A2Cou
Transgene Detail

Summary

• Symbol: Tg(KRT16/KRT14)A2Cou
• Name: transgene insertion A2, Pierre Coulombe
• MGI ID: MGI:1926506
• Synonyms: K16-C14
• Transgene: Tg(KRT16/KRT14)A2Cou Location: unknown
• Alliance: Tg(KRT16/KRT14)A2Cou page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT16/KRT14)A2Cou expresses 2 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  KRT14 (3861)

  Krt14

  (MGI:96688)

  human

  KRT16 (3868)

  Krt16

  (MGI:96690)

• Mutation details: Overexpression of a human keratin 16 (KRT16) and human keratin 14 (KRT14) chimeric gene in the basal layer of the epidermis, driven by the human keratin 14 (KRT14) promoter. (J:49421)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Founder number A2 is representative of a number of founders that were examined and found to be phenotypically normal. The other founder numbers were designated B1 and C1.

References

• Original: J:49421 Paladini RD, et al., Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation. J Cell Biol. 1998 Aug 24;142(4):1035-51
• All: 3 reference(s)