Sme
Radiation induced Allele Detail

Summary

• Symbol: Sme
• Name: small ear
• MGI ID: MGI:1861503
• Gene: Sme Location: unknown
• Alliance: Sme page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Radiation induced
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sme Mutation: 0 strains or lines available

Notes

Reduced ear pinna size was found in descendants of males treated with triethylenemelamine and X-irradiation. Ear size in heterozygotes is variable, and may be bilaterally asymetrical. Ear shape is often irregular. There is a shortage of Sme/+ heterozygotes at weaning, but not at birth, due to postnatal mortality. Homozygous mutant mice show no or very small ear pinnae. They appear to die perinatally with cleft palates and other abnormalities (J:14271).

References

• Original: J:14271 Rasberry C, et al., Small ear, a new dominant mutation. Mouse News Lett. 1988;80:158-9
• All: 2 reference(s)