Slc45a2^uw-d
Spontaneous Allele Detail

Summary

• Symbol: Slc45a2^uw-d
• Name: solute carrier family 45, member 2; underwhite dense
• MGI ID: MGI:1857540
• Gene: Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
• Alliance: Slc45a2^uw-d page

Mutation origin

• Strain of Origin: TF/Le

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Molecular analysis reveals a T-to-C transition in codon 435, resulting in a serine to proline substitution (p.S435P) within transmembrane domain 10 of the protein. (J:72440)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slc45a2 Mutation: 55 strains or lines available

References

• Original: J:41299 Sweet HO, et al., A new allelic series for the underwhite gene on mouse chromosome 15. J Hered. 1998 Nov-Dec;89(6):546-51
• All: 4 reference(s)