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Eedl7Rn5-3354SB
Chemically induced Allele Detail
Summary
Symbol: Eedl7Rn5-3354SB
Name: embryonic ectoderm development; lethal, Chr 7, Rinchik 5, 3354SB
MGI ID: MGI:1856856
Synonyms: 17Rn53354SB, 3354SB, Eed-, eed3354, Eedl7Rn5-3R, eednull
Gene: Eed  Location: Chr7:89603862-89630184 bp, - strand  Genetic Position: Chr7, 50.42 cM
Alliance: Eedl7Rn5-3354SB page
Mutation
origin
Strain of Origin:  BALB/cRl
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsPositional cloning of the embryonic ectoderm development locus identified a transition of thymine at position 1040 to cytosine in the 3354SB ENU induced allele. The amino acid change of a Leu to a Pro at amino acid position 196 lies the second WD motif. (J:35419)
Inheritance:    Recessive
Expression
In Mice Carrying this Mutation: 41 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Eed Mutation:  116 strains or lines available
References
Original:  J:12917 Rinchik EM, et al., N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7. Mamm Genome. 1993;4(7):349-53
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory