t^Tu1
Spontaneous Allele Detail

Summary

• Symbol: t^Tu1
• Name: t-complex; t, Tubingen 1
• MGI ID: MGI:1856770
• Gene: t Location: unknown Genetic Position: Chr17, Syntenic
• Alliance: t^Tu1 page

Mutation origin

• Strain of Origin: STOCK + t^w12 Itpr3^tf H2^w30/Rb(16.17)7Bnr + + H2^d x + + + H2^b/+ + + H2^b

Mutation description

• Allele Type: Spontaneous
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any t Mutation: 19 strains or lines available

Notes

Robertsonian Rb7 is Rb(16.17)Bnr. t^Tu1 originated with a crossing-over event between the centromere and the H-2 complex producing an exceptional male having a normal tail and lacking Rb7, but carrying H-2^d, suggesting that one Chr 17 comprised the centromeric portion of the t^w12 haplotype and the telomeric portion of the Rb17 chromosome.

References

• Original: J:6700 Styrna J, et al., Evidence for two regions in the mouse t complex controlling transmission ratios. Genet Res. 1981 Dec;38(3):315-25
• All: 2 reference(s)