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Gene Expression Data
Assay Details
Assay
Reference: J:198427 Dudok JJ, et al., MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8325728
Gene symbol: Pals1
Gene name: protein associated with LIN7 1, MAGUK family member
Antibody: anti-MPP5 (SN47)
Detection system: Secondary antibody
Assay notes: There was another antibody mentioned in the paper. It was not specified which one was used.
Results
Specimen 4C/E: embryonic day 12.5; Emx1tm1(cre)Ito/Emx1+, Mpp3tm1.1Wij/Mpp3+ (more )
Note: Conditional mutant. Double labeled: red - Pals1; green - Mpp3 (assay MGI:8325724).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present Regionally restricted 4E , 4C Expressed at the most apical side.
Specimen 4D/F: embryonic day 12.5; Mpp3tm1.1Wij/Mpp3tm1.1Wij, Emx1tm1(cre)Ito/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Pals1; green - Mpp3 (assay MGI:8325724).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present Regionally restricted 4F , 4D Reduced expression at the apical membrane, compared with control cortex.
Specimen 4G: embryonic day 12.5; Mpp3tm1.1Wij/Mpp3tm1.1Wij, Emx1tm1(cre)Ito/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Pals1; green - Mpp3 (assay MGI:8325724).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present Non-Uniform 4G At areas with remaining Mpp3 expression, Pals1 levels were unchanged, whereas at areas with reduced Mpp3, Pals1 levels were decreased.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
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