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Gene Expression Data
Assay Details
Assay
Reference: J:232175 Diaz-Horta O, et al., ROR1 is essential for proper innervation of auditory hair cells and hearing in humans and mice. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5993-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8291851
Gene symbol: Ror1
Gene name: receptor tyrosine kinase-like orphan receptor 1
Antibody: Anti-Ror1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3A: embryonic day 14.5 (more )
Note: Triple labeled: green - Ror1; red - Myo7a (assay MGI:8291852); pink - Nefh (assay MGI:8291837).
Structure Level Pattern Image Note
TS22: cochlear ganglion Present 3A left , 3A center
TS22: cochlea epithelium Present Non-Uniform 3A center , 3A right
Specimen 3B: embryonic day 17.5 (more )
Note: Triple labeled: green - Ror1; red - Myo7a (assay MGI:8291852); pink - Nefh (assay MGI:8291837).
Structure Level Pattern Image Note
TS25: cochlear ganglion Present 3B center , 3B left
TS25: organ of Corti Present Regionally restricted 3B right , 3B center Ror1 signals gain intensity in spiral ganglion neuron axon terminals adjacent to auditory hair cells.
TS25: cochlea epithelium Present Regionally restricted 3B center , 3B right In the differentiating cochlear epithelium, Ror1 expression was intense in the stria vascularis.
Specimen 3C: postnatal day 0 (more )
Note: Triple labeled: green - Ror1; red - Myo7a (assay MGI:8291852); pink - Nefh (assay MGI:8291837).
Structure Level Pattern Image Note
TS27: cochlear ganglion Present 3C left , 3C center
TS27: organ of Corti Present Regionally restricted 3C center , 3C right Expression was detected in spiral ganglion neuron axon terminals.
TS27: stria vascularis Weak 3C right , 3C center
Specimen S8A: embryonic day 14.5 (more )
Note: Triple labeled: green - Ror1; red - Myo7a; pink - Nefh.
Structure Level Pattern Image Note
TS22: inner ear vestibular component Present S8A Ror1 is expressed in the vestibule at this embryonic stage.
Specimen S8B: postnatal day 0; Ror1tm1Ymi/Ror1tm1Ymi (more )
Note: Triple labeled: green - Ror1; red - Myo7a; pink - Nefh.
Structure Level Pattern Image Note
TS27: cochlear ganglion Absent S8B
TS27: stria vascularis Absent S8B
TS27: organ of Corti Absent S8B Signal was not detectable in the mutant spiral ganglion nerve axon terminals.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory