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Gene Expression Data
Assay Details
Assay
Reference: J:372756 Wang YJ, et al., PRMT5-mediated homologous recombination repair is essential to maintain genomic integrity of neural progenitor cells. Cell Mol Life Sci. 2024 Mar 8;81(1):123
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8288289
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Results
Specimen 1L WT: postnatal day 10 (more )
Note: Double labeled: red - Bcl11b; green - Cux1 (assay MGI:8288288).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 1L WT Medial , 1L WT , 1L WT Lateral Expression in deep layer.
Specimen 1L cKO-Emx1: postnatal day 10; Emx1tm1(cre)Krj/Emx1+, Prmt5tm2c(EUCOMM)Wtsi/Prmt5tm2c(EUCOMM)Wtsi (more )
Note: Conditional mutant. Double labeled: red - Bcl11b; green - Cux1 (assay MGI:8288288).
Structure Level Pattern Image Note
TS28: cerebral cortex Present Regionally restricted 1L cKO-Emx1 , 1L cKO-Emx1 Medial , 1L cKO-Emx1 Lateral Thickness of deep layer sharply reduced compared to wild type.
Specimen S1K WT: postnatal day 10 (more )
Note: Double labeled: red - Bcl11b; green - Cux1 (assay MGI:8288288).
Structure Level Pattern Image Note
TS28: cerebral cortex Present S1K WT
Specimen S1K cKO-Nes: postnatal day 10; Neurod6tm1(cre)Kan/Neurod6+, Prmt5tm2c(EUCOMM)Wtsi/Prmt5tm2c(EUCOMM)Wtsi (more )
Note: Conditional mutant. Double labeled: red - Bcl11b; green - Cux1 (assay MGI:8288288).
Structure Level Pattern Image Note
TS28: cerebral cortex Present S1K cKO-Nex Authors report no visible defects compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory