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Gene Expression Data
Assay Details
Assay
Reference: J:370213 Windley SP, et al., NEDD4 Promotes Sertoli Cell Proliferation and Adult Leydig Cell Differentiation in the Murine Testis. Endocrinology. 2025 Jul 8;166(9)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8233771
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox9
Results
Specimen 1A SOX9 Control middle: embryonic day 11.5; Nedd4tm3.1Bros/? (more )
Note: Double labeled: green - Sox9; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS19: gonad Sertoli cell Present 1A Control middle
Specimen 1A SOX9 Cre;flox/flox middle: embryonic day 11.5; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: green - Sox9; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS19: gonad Sertoli cell Present 1A Cre:flox/flox middle Normal expression compared to control.
Specimen 1B SOX9 Control middle: embryonic day 12.5; Nedd4tm3.1Bros/? (more )
Note: Double labeled: green - Sox9; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS20: Sertoli cell Sertoli cell Present 1B Control middle
Specimen 1B SOX9 Cre;flox/flox middle: embryonic day 12.5; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: green - Sox9; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS20: Sertoli cell Sertoli cell Present 1B Cre:flox/flox middle
Specimen 2A SOX9: embryonic day 14.5; Nedd4tm3.1Bros/? (more )
Note: Double labeled: green - Sox9; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present Regionally restricted 2A Expression in Sertoli cells successfully forming testis cords enclosing germ cells.
Specimen 2F SOX9: embryonic day 14.5; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: green - Sox9; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present Regionally restricted 2F Expression in Sertoli cells successfully forming testis cords enclosing germ cells.
Specimen S1C SOX9 Control: embryonic day 14.5; Nedd4tm3.1Bros/? (more )
Note: Double labeled: magenta - Sox9; green - Nedd4 (assay MGI:8233776).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present S1C Control
Specimen S1C SOX9 Cre;flox/flox: embryonic day 14.5; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: magenta - Sox9; green - Nedd4 (assay MGI:8233776).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present S1C Cre:flox/flox
Specimen 3E SOX9: postnatal day 60; Nedd4tm3.1Bros/? (more )
Note: Double labeled: green - Sox9; magenta - Foxl2 (assay MGI:8233774).
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present Regionally restricted 3E Expression in Sertoli cells lining basement membrane of seiminferous tubules.
Specimen 3F SOX9: postnatal day 60; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: green - Sox9; magenta - Foxl2 (assay MGI:8233774).
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present Regionally restricted 3F Expression in Sertoli cells lining basement membrane of seiminferous tubules.
Specimen 3H SOX9 Control: embryonic day 15.5; Nedd4tm3.1Bros/? (more )
Note: Double labeled: magenta - Sox9; green - Mki67 (assay MGI:8233786).
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present Regionally restricted 3H Control Expression in Sertoli cells lining basement membrane of seiminferous tubules.
Specimen 3H SOX9 Cre;flox/flox: embryonic day 15.5; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: magenta - Sox9; green - Mki67 (assay MGI:8233786).
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 3H Cre:flox/flox Authors report 42.1% fewer proliferative Sertoli cells compared to control.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
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