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Gene Expression Data
Assay Details
Assay
Reference: J:370213 Windley SP, et al., NEDD4 Promotes Sertoli Cell Proliferation and Adult Leydig Cell Differentiation in the Murine Testis. Endocrinology. 2025 Jul 8;166(9)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8233769
Gene symbol: Sry
Gene name: sex determining region of Chr Y
Antibody: Anti-Sry
Results
Specimen 1A SRY Control left: embryonic day 11.5; Nedd4tm3.1Bros/? (more )
Note: Double labeled: green - Sry; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS19: gonad Sertoli cell Present 1A Control left
Specimen 1A SRY Cre;flox/flox left: embryonic day 11.5; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: green - Sry; magenta - Ddx4 (assay MGI:8233768).
Structure Level Pattern Image Note
TS19: gonad Present 1A Cre:flox/flox left Normal expression compared to control.
Specimen 1B SRY Control left: embryonic day 12.5; Nedd4tm3.1Bros/? (more )
Note: Double labeled: green - Sry; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS20: Sertoli cell Sertoli cell Weak 1B Control left Expression downregulated compared to E11.5.
Specimen 1B SRY Cre;flox/flox left: embryonic day 12.5; Nedd4tm3.1Bros/Nedd4tm3.1Bros, Tg(Nr5a1-cre)2Klp/0 (more )
Note: Conditional mutant. Double labeled: green - Sry; magenta - Ddx4 (assay MGI:8233768).
Structure Cell Type Level Pattern Image Note
TS20: Sertoli cell Sertoli cell Weak 1B Cre:flox/flox left Expression downregulated compared to E11.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory