About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:245758 Carreno G, et al., Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors. Development. 2017 Sep 15;144(18):3289-3302
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8174555
Gene symbol: Cdh2
Gene name: cadherin 2
Results
Specimen 5U: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shh+ (more )
Note: Conditional mutant. Double labeled: green - Cdh2; red - Cdh1 (assay MGI:8174581).
Structure Level Pattern Image Note
TS17: diencephalon Present Regionally restricted 5U Expression is detected in the hypothalamus in the control embryos.
TS17: Rathke's pouch Present 5U
Specimen 5V: embryonic day 10.5; Hesx1tm1(cre)Jpmb/Hesx1+, Shhtm2Amc/Shhtm2.1Amc (more )
Note: Conditional mutant. Double labeled: green - Cdh2; red - Cdh1 (assay MGI:8174581).
Structure Level Pattern Image Note
TS17: diencephalon Present 5V Expression in the mutant hypothalamus is comparable to the control.
TS17: Rathke's pouch Present Regionally restricted 5V Anterior expression was lost in the mutant Rathke's pouch, which ectopically expressed E-cadherin.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory